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Blood Makes a Difference: Experimental Evaluation of Molecular Communication in Different Fluids

Journal article

Fast facts

  • Further publishers

    Lisa Debus, Mario J. Wilhelm, Henri Wolff, Luiz C. P. Wille, Tim Rese, Michael Lommel, Falko Dressler

  • Publishment

    • IEEE (New York, NY) 2025
  • Purpose of publication

  • Organizational unit

  • Subjects

    • Biomedical technology
    • Communication and information technology
    • Medical physics
  • Research structures

    • BioMedicalTechnology (BMT)
  • Research fields

    • Information technology
    • Micro- and nanosystems
    • Scientific research

Quote

L. Debus, M. J. Wilhelm, H. Wolff, L. C. P. Wille, T. Rese, M. Lommel, J. Kirchner, and F. Dressler, "Blood Makes a Difference: Experimental Evaluation of Molecular Communication in Different Fluids," IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, 2025.

Content

The experimental appraisal of existing molecular communication (MC) testbeds and modeling frameworks in real blood is an important step for future internet of bio-nano things applications. In this paper, we experimentally compare the MC flow characteristics of water, blood substitute, and real porcine blood for a previously presented superparamagnetic iron oxide nanoparticles (SPION) MC testbed. We perform an extensive analysis of the channel impulse response (CIR) behavior of the testbed for the different fluids. Based on the identified MC flow characteristics, we extend an existing mathematical framework for our SPION testbed to capture the flow properties of blood. We evaluate its applicability to the collected data in comparison to two existing theoretical CIR models for MC in blood. In our work, we see that the added complexity of the transmission in blood opens up promising new possibilities to improve communication through the human circulatory system.

References

DOI 10.1109/TMBMC.2025.3602650

Notes and references

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